Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline
Identifieur interne : 004D47 ( Main/Exploration ); précédent : 004D46; suivant : 004D48Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline
Auteurs : Alexander Yaw Debrah ; Sabine Mand [Allemagne] ; Yeboah Marfo-Debrekyei [Ghana] ; Linda Batsa [Ghana] ; Anna Albers [Allemagne] ; Sabine Specht [Allemagne] ; Ute Klarmann [Allemagne] ; Kenneth Pfarr [Allemagne] ; Ohene Adjei [Ghana] ; Achim Hoerauf [Allemagne]Source :
- Journal of Parasitology Research [ 2090-0023 ] ; 2011.
Abstract
Infection with the filarial nematode
Url:
DOI: 10.1155/2011/201617
PubMed: 21687646
PubMed Central: 3112504
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 004111
- to stream Pmc, to step Curation: 004110
- to stream Pmc, to step Checkpoint: 002E73
- to stream PubMed, to step Corpus: 002575
- to stream PubMed, to step Curation: 002575
- to stream PubMed, to step Checkpoint: 002575
- to stream Ncbi, to step Merge: 004447
- to stream Ncbi, to step Curation: 004447
- to stream Ncbi, to step Checkpoint: 004447
- to stream Main, to step Merge: 004D82
- to stream Main, to step Curation: 004D47
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Macrofilaricidal Activity in <italic>Wuchereria bancrofti</italic> after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline</title><author><name sortKey="Debrah, Alexander Yaw" sort="Debrah, Alexander Yaw" uniqKey="Debrah A" first="Alexander Yaw" last="Debrah">Alexander Yaw Debrah</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Mand, Sabine" sort="Mand, Sabine" uniqKey="Mand S" first="Sabine" last="Mand">Sabine Mand</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Marfo Debrekyei, Yeboah" sort="Marfo Debrekyei, Yeboah" uniqKey="Marfo Debrekyei Y" first="Yeboah" last="Marfo-Debrekyei">Yeboah Marfo-Debrekyei</name><affiliation wicri:level="1"><nlm:aff id="I2">Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Batsa, Linda" sort="Batsa, Linda" uniqKey="Batsa L" first="Linda" last="Batsa">Linda Batsa</name><affiliation wicri:level="1"><nlm:aff id="I2">Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Albers, Anna" sort="Albers, Anna" uniqKey="Albers A" first="Anna" last="Albers">Anna Albers</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Specht, Sabine" sort="Specht, Sabine" uniqKey="Specht S" first="Sabine" last="Specht">Sabine Specht</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Klarmann, Ute" sort="Klarmann, Ute" uniqKey="Klarmann U" first="Ute" last="Klarmann">Ute Klarmann</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Pfarr, Kenneth" sort="Pfarr, Kenneth" uniqKey="Pfarr K" first="Kenneth" last="Pfarr">Kenneth Pfarr</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Adjei, Ohene" sort="Adjei, Ohene" uniqKey="Adjei O" first="Ohene" last="Adjei">Ohene Adjei</name><affiliation wicri:level="1"><nlm:aff id="I4">School of Medical Sciences, Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>School of Medical Sciences, Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Hoerauf, Achim" sort="Hoerauf, Achim" uniqKey="Hoerauf A" first="Achim" last="Hoerauf">Achim Hoerauf</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21687646</idno><idno type="pmc">3112504</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112504</idno><idno type="RBID">PMC:3112504</idno><idno type="doi">10.1155/2011/201617</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">004111</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004111</idno><idno type="wicri:Area/Pmc/Curation">004110</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004110</idno><idno type="wicri:Area/Pmc/Checkpoint">002E73</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002E73</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002575</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002575</idno><idno type="wicri:Area/PubMed/Curation">002575</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002575</idno><idno type="wicri:Area/PubMed/Checkpoint">002575</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002575</idno><idno type="wicri:Area/Ncbi/Merge">004447</idno><idno type="wicri:Area/Ncbi/Curation">004447</idno><idno type="wicri:Area/Ncbi/Checkpoint">004447</idno><idno type="wicri:doubleKey">2090-0023:2011:Debrah A:macrofilaricidal:activity:in</idno><idno type="wicri:Area/Main/Merge">004D82</idno><idno type="wicri:Area/Main/Curation">004D47</idno><idno type="wicri:Area/Main/Exploration">004D47</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Macrofilaricidal Activity in <italic>Wuchereria bancrofti</italic> after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline</title><author><name sortKey="Debrah, Alexander Yaw" sort="Debrah, Alexander Yaw" uniqKey="Debrah A" first="Alexander Yaw" last="Debrah">Alexander Yaw Debrah</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Mand, Sabine" sort="Mand, Sabine" uniqKey="Mand S" first="Sabine" last="Mand">Sabine Mand</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Marfo Debrekyei, Yeboah" sort="Marfo Debrekyei, Yeboah" uniqKey="Marfo Debrekyei Y" first="Yeboah" last="Marfo-Debrekyei">Yeboah Marfo-Debrekyei</name><affiliation wicri:level="1"><nlm:aff id="I2">Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Batsa, Linda" sort="Batsa, Linda" uniqKey="Batsa L" first="Linda" last="Batsa">Linda Batsa</name><affiliation wicri:level="1"><nlm:aff id="I2">Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Albers, Anna" sort="Albers, Anna" uniqKey="Albers A" first="Anna" last="Albers">Anna Albers</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Specht, Sabine" sort="Specht, Sabine" uniqKey="Specht S" first="Sabine" last="Specht">Sabine Specht</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Klarmann, Ute" sort="Klarmann, Ute" uniqKey="Klarmann U" first="Ute" last="Klarmann">Ute Klarmann</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Pfarr, Kenneth" sort="Pfarr, Kenneth" uniqKey="Pfarr K" first="Kenneth" last="Pfarr">Kenneth Pfarr</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Adjei, Ohene" sort="Adjei, Ohene" uniqKey="Adjei O" first="Ohene" last="Adjei">Ohene Adjei</name><affiliation wicri:level="1"><nlm:aff id="I4">School of Medical Sciences, Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>School of Medical Sciences, Kwame Nkrumah University of Science and Technology, UPO, PMB, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Hoerauf, Achim" sort="Hoerauf, Achim" uniqKey="Hoerauf A" first="Achim" last="Hoerauf">Achim Hoerauf</name><affiliation wicri:level="1"><nlm:aff id="I3">Institute for Medical Microbiology, Immunology and Parasitology, University Clinic Bonn, Sigmund-Freud-Stra<italic>β</italic>e 25, D-53105 Bonn, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>e 25, D-53105 Bonn</wicri:regionArea><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>53105 Bonn</wicri:noRegion><wicri:noRegion>D-53105 Bonn</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Parasitology Research</title><idno type="ISSN">2090-0023</idno><idno type="eISSN">2090-0031</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Infection with the filarial nematode <italic>Wuchereria bancrofti</italic> can lead to lymphedema, hydrocele, and elephantiasis. Since adult worms cause pathology in lymphatic filariasis (LF), it is imperative to discover macrofilaricidal drugs for the treatment of the infection. Endosymbiotic <italic>Wolbachia</italic> in filariae have emerged as a new target for antibiotics which can lead to macrofilaricidal effects. In Ghana, a pilot study was carried out with 39 LF-infected men; 12 were treated with 200 mg doxycycline/day for 4 weeks, 16 were treated with a combination of 200 mg doxycycline/day + 10 mg/kg/day rifampicin for 2 weeks, and 11 patients received placebo. Patients were monitored for <italic>Wolbachia</italic> and microfilaria loads, antigenaemia, and filarial dance sign (FDS). Both 4-week doxycycline and the 2-week combination treatment reduced <italic>Wolbachia</italic> load significantly. At 18 months posttreatment, four-week doxycycline resulted in 100% adult worm loss, and the 2-week combination treatment resulted in a 50% adult worm loss. In conclusion, this pilot study with a combination of 2-week doxycycline and rifampicin demonstrates moderate macrofilaricidal activity against <italic>W. bancrofti</italic>.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Awadzi, K" uniqKey="Awadzi K">K Awadzi</name></author><author><name sortKey="Attah, Sk" uniqKey="Attah S">SK Attah</name></author><author><name sortKey="Addy, Et" uniqKey="Addy E">ET Addy</name></author><author><name sortKey="Opoku, No" uniqKey="Opoku N">NO Opoku</name></author><author><name sortKey="Quartey, Bt" uniqKey="Quartey B">BT Quartey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ottesen, Ea" uniqKey="Ottesen E">EA Ottesen</name></author><author><name sortKey="Duke, Bol" uniqKey="Duke B">BOL Duke</name></author><author><name sortKey="Karam, M" uniqKey="Karam M">M Karam</name></author><author><name sortKey="Behbehani, K" uniqKey="Behbehani K">K Behbehani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nor Es, J" uniqKey="Nor Es J">J Norões</name></author><author><name sortKey="Dreyer, G" uniqKey="Dreyer G">G Dreyer</name></author><author><name sortKey="Santos, A" uniqKey="Santos A">A Santos</name></author><author><name sortKey="Mendes, Vg" uniqKey="Mendes V">VG Mendes</name></author><author><name sortKey="Medeiros, Z" uniqKey="Medeiros Z">Z Medeiros</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Critchley, J" uniqKey="Critchley J">J Critchley</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author><author><name sortKey="Gamble, C" uniqKey="Gamble C">C Gamble</name></author><author><name sortKey="Garner, P" uniqKey="Garner P">P Garner</name></author><author><name sortKey="Gelband, H" uniqKey="Gelband H">H Gelband</name></author><author><name sortKey="Ejere, H" uniqKey="Ejere H">H Ejere</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gyapong, Jo" uniqKey="Gyapong J">JO Gyapong</name></author><author><name sortKey="Kumaraswami, V" uniqKey="Kumaraswami V">V Kumaraswami</name></author><author><name sortKey="Biswas, G" uniqKey="Biswas G">G Biswas</name></author><author><name sortKey="Ottesen, Ea" uniqKey="Ottesen E">EA Ottesen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dreyer, G" uniqKey="Dreyer G">G Dreyer</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author><author><name sortKey="Williamson, J" uniqKey="Williamson J">J Williamson</name></author><author><name sortKey="Nor Es, J" uniqKey="Nor Es J">J Norões</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Volkmann, L" uniqKey="Volkmann L">L Volkmann</name></author><author><name sortKey="Hamelmann, C" uniqKey="Hamelmann C">C Hamelmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Adjei, O" uniqKey="Adjei O">O Adjei</name></author><author><name sortKey="Fleischer, B" uniqKey="Fleischer B">B Fleischer</name></author><author><name sortKey="Buttner, Dw" uniqKey="Buttner D">DW Büttner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Specht, S" uniqKey="Specht S">S Specht</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Debrah, Ay" uniqKey="Debrah A">AY Debrah</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author><author><name sortKey="Larbi, J" uniqKey="Larbi J">J Larbi</name></author><author><name sortKey="Adjei, O" uniqKey="Adjei O">O Adjei</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, Mj" uniqKey="Taylor M">MJ Taylor</name></author><author><name sortKey="Makunde, Wh" uniqKey="Makunde W">WH Makunde</name></author><author><name sortKey="Mcgarry, Hf" uniqKey="Mcgarry H">HF McGarry</name></author><author><name sortKey="Turner, Jd" uniqKey="Turner J">JD Turner</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Debrah, Ay" uniqKey="Debrah A">AY Debrah</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Specht, S" uniqKey="Specht S">S Specht</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Debrah, Ay" uniqKey="Debrah A">AY Debrah</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Debrah, Ay" uniqKey="Debrah A">AY Debrah</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Turner, Jd" uniqKey="Turner J">JD Turner</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Debrah, Ay" uniqKey="Debrah A">AY Debrah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Pfarr, K" uniqKey="Pfarr K">K Pfarr</name></author><author><name sortKey="Sahoo, Pk" uniqKey="Sahoo P">PK Sahoo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Townson, S" uniqKey="Townson S">S Townson</name></author><author><name sortKey="Hutton, D" uniqKey="Hutton D">D Hutton</name></author><author><name sortKey="Siemienska, J" uniqKey="Siemienska J">J Siemienska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rao, R" uniqKey="Rao R">R Rao</name></author><author><name sortKey="Weil, Gj" uniqKey="Weil G">GJ Weil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Volkmann, L" uniqKey="Volkmann L">L Volkmann</name></author><author><name sortKey="Fischer, K" uniqKey="Fischer K">K Fischer</name></author><author><name sortKey="Taylor, M" uniqKey="Taylor M">M Taylor</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Specht, S" uniqKey="Specht S">S Specht</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Fischer, K" uniqKey="Fischer K">K Fischer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Marfo Debrekyei, Y" uniqKey="Marfo Debrekyei Y">Y Marfo-Debrekyei</name></author><author><name sortKey="Dittrich, M" uniqKey="Dittrich M">M Dittrich</name></author><author><name sortKey="Fischer, K" uniqKey="Fischer K">K Fischer</name></author><author><name sortKey="Adjei, O" uniqKey="Adjei O">O Adjei</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dreyer, G" uniqKey="Dreyer G">G Dreyer</name></author><author><name sortKey="Brandao, Ac" uniqKey="Brandao A">AC Brandão</name></author><author><name sortKey="Amaral, F" uniqKey="Amaral F">F Amaral</name></author><author><name sortKey="Medeiros, Z" uniqKey="Medeiros Z">Z Medeiros</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mand, S" uniqKey="Mand S">S Mand</name></author><author><name sortKey="Buttner, Dw" uniqKey="Buttner D">DW Büttner</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kshirsagar, Na" uniqKey="Kshirsagar N">NA Kshirsagar</name></author><author><name sortKey="Gogtay, Nj" uniqKey="Gogtay N">NJ Gogtay</name></author><author><name sortKey="Garg, Bs" uniqKey="Garg B">BS Garg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nor Es, J" uniqKey="Nor Es J">J Norões</name></author><author><name sortKey="Dreyer, G" uniqKey="Dreyer G">G Dreyer</name></author><author><name sortKey="Santos, A" uniqKey="Santos A">A Santos</name></author><author><name sortKey="Mendes, Vg" uniqKey="Mendes V">VG Mendes</name></author><author><name sortKey="Medeiros, Z" uniqKey="Medeiros Z">Z Medeiros</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ottesen, Ea" uniqKey="Ottesen E">EA Ottesen</name></author><author><name sortKey="Duke, Bol" uniqKey="Duke B">BOL Duke</name></author><author><name sortKey="Karam, M" uniqKey="Karam M">M Karam</name></author><author><name sortKey="Behbehani, K" uniqKey="Behbehani K">K Behbehani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hussein, O" uniqKey="Hussein O">O Hussein</name></author><author><name sortKey="El Setouhy, M" uniqKey="El Setouhy M">M El Setouhy</name></author><author><name sortKey="Ahmed, Es" uniqKey="Ahmed E">ES Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dreyer, G" uniqKey="Dreyer G">G Dreyer</name></author><author><name sortKey="Addiss, D" uniqKey="Addiss D">D Addiss</name></author><author><name sortKey="Williamson, J" uniqKey="Williamson J">J Williamson</name></author><author><name sortKey="Nor Es, J" uniqKey="Nor Es J">J Norões</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, Mj" uniqKey="Taylor M">MJ Taylor</name></author><author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name></author><author><name sortKey="Bockarie, M" uniqKey="Bockarie M">M Bockarie</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Ghana</li></country></list><tree><noCountry><name sortKey="Debrah, Alexander Yaw" sort="Debrah, Alexander Yaw" uniqKey="Debrah A" first="Alexander Yaw" last="Debrah">Alexander Yaw Debrah</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Mand, Sabine" sort="Mand, Sabine" uniqKey="Mand S" first="Sabine" last="Mand">Sabine Mand</name></noRegion><name sortKey="Albers, Anna" sort="Albers, Anna" uniqKey="Albers A" first="Anna" last="Albers">Anna Albers</name><name sortKey="Hoerauf, Achim" sort="Hoerauf, Achim" uniqKey="Hoerauf A" first="Achim" last="Hoerauf">Achim Hoerauf</name><name sortKey="Klarmann, Ute" sort="Klarmann, Ute" uniqKey="Klarmann U" first="Ute" last="Klarmann">Ute Klarmann</name><name sortKey="Pfarr, Kenneth" sort="Pfarr, Kenneth" uniqKey="Pfarr K" first="Kenneth" last="Pfarr">Kenneth Pfarr</name><name sortKey="Specht, Sabine" sort="Specht, Sabine" uniqKey="Specht S" first="Sabine" last="Specht">Sabine Specht</name></country><country name="Ghana"><noRegion><name sortKey="Marfo Debrekyei, Yeboah" sort="Marfo Debrekyei, Yeboah" uniqKey="Marfo Debrekyei Y" first="Yeboah" last="Marfo-Debrekyei">Yeboah Marfo-Debrekyei</name></noRegion><name sortKey="Adjei, Ohene" sort="Adjei, Ohene" uniqKey="Adjei O" first="Ohene" last="Adjei">Ohene Adjei</name><name sortKey="Batsa, Linda" sort="Batsa, Linda" uniqKey="Batsa L" first="Linda" last="Batsa">Linda Batsa</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004D47 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004D47 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3112504
|texte= Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21687646" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |